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Lupeol acetate

CAT: 0804-HY-126114-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126114-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility[1][2][3][4].
CAS Number
1617-68-1
UNSPSC
12352211
Target
Bacterial; COX; Fungal; Interleukin Related; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lupeol-acetate.html
Purity
98.0
Solubility
Ethanol : ≥ 2 mg/mL
Smiles
C[C@@]([C@@]1(CC[C@@]2([H])C3(C)C)C)(CC4)[C@@](CC[C@]1([H])[C@]2(CC[C@@H]3OC(C)=O)C)([H])[C@]([C@@H]5C(C)=C)([H])[C@@]4(CC5)C
Molecular Formula
C32H52O2
Molecular Weight
468.75
References & Citations
[1]Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.|[2]Javed S, et al. Lupeol acetate as a potent antifungal compound against opportunistic human and phytopathogenic mold Macrophomina phaseolina. Sci Rep. 2021 Apr 19;11 (1) :8417. |[3]Pardo-Rodriguez D, et al. Lupeol Acetate and α-Amyrin Terpenes Activity against Trypanosoma cruzi: Insights into Toxicity and Potential Mechanisms of Action. Trop Med Infect Dis. 2023 May 3;8 (5) :263.|[4]Gupta RS, et al. Induction of antifertility with lupeol acetate in male albino rats. Pharmacology. 2005 Oct;75 (2) :57-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2

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