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(-) -Menthol-d4

CAT: 0804-HY-W711474-02Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W711474-02Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Menthol-d4 is the deuterium labeled (-) -Menthol. (-) -Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i[1]. Antitumor activity[1].
CAS Number
1450828-98-4
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@]1([C@@]([2H])(CC[C@H](C1([2H])[2H])C)C(C)C)[2H]
Molecular Formula
C10H16D4O
Molecular Weight
160.29
References & Citations
[1]Park EJ, et al. Menthol Enhances an Antiproliferative Activity of 1alpha,25-Dihydroxyvitamin D (3) in LNCaP Cells. J Clin Biochem Nutr. 2009 Mar;44 (2) :125-30.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Chemical Information

(1R,2S,5R)-(-)-Menthol-d4
CAS Number1450828-98-4
PubChem CID154825536
IUPAC Name(1R,3R,6S)-1,2,2,6-tetradeuterio-3-methyl-6-propan-2-ylcyclohexan-1-ol
Molecular FormulaC10H20O
Molecular Weight160.29
XLogP3
Topological Polar Surface Area20.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Heavy Atom Count11
Formal Charge0
Complexity120
SMILES
[2H][C@]1(CC[C@H](C([C@@]1([2H])O)([2H])[2H])C)C(C)C
InChI
InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1/i6D2,9D,10D
InChIKey
NOOLISFMXDJSKH-JVBCQMCMSA-N
Chemical Structure
2D Structure
2D structure of (1R,2S,5R)-(-)-Menthol-d4
CAS: 1450828-98-4
CID: 154825536
Formula: C10H20O
MW: 160.29
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight160.29
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass160.176522241
Monoisotopic Mass160.176522241
Topological Polar Surface Area20.2 Ų
Heavy Atom Count11
Formal Charge0
Complexity120
Isotope Atom Count4
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes