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T-1032 (free base)

CAT: 0804-HY-W705784Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W705784Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
T-1032 free base is a selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 1.0 nM. T-1032 free base shows relaxant effect on isolated rabbit corpus cavernosum. T-1032 free base can be used for the research of erectile dysfunction[1].
CAS Number
212500-02-2
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C(N(C(C(OC)=O)=C1C2=CC(OC)=C(C(OC)=C2)OC)C3=CC=C(C=C3)N)C4=C1C=CC(OCC5=CC=CC=N5)=C4
Molecular Formula
C32H29N3O7
Molecular Weight
567.59
References & Citations
[1]Ukita T, et al. Novel, potent, and selective phosphodiesterase 5 inhibitors: synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives. J Med Chem. 2001 Jun 21;44 (13) :2204-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5

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