T-1032 (free base)

• Description:

  T-1032 free base is a selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 1.0 nM. T-1032 free base shows relaxant effect on isolated rabbit corpus cavernosum. T-1032 free base can be used for the research of erectile dysfunction[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Smiles:

  O=C(N(C(C(OC)=O)=C1C2=CC(OC)=C(C(OC)=C2)OC)C3=CC=C(C=C3)N)C4=C1C=CC(OCC5=CC=CC=N5)=C4

• Molecular Formula:

  C32H29N3O7

• Molecular Weight:

  567.59

• References & Citations:

  [1]Ukita T, et al. Novel, potent, and selective phosphodiesterase 5 inhibitors: synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives. J Med Chem. 2001 Jun 21;44 (13) :2204-18.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PDE5

• CAS Number:

  [212500-02-2]