(Rac) -BX 048

• Description:

  (Rac) -BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid (HY-109590) induced platelet aggregation (IC50 of 15 μM) [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  P2Y Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C (O) CCC (NC (C1=NC2=CC (C) =CC=C2C (OC (C) (C) C (O) =O) =C1) =O) C (N3CCN (C (OCC) =O) CC3) =O

• Molecular Formula:

  C27H34N4O9

• Molecular Weight:

  558.58

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Post JM, et al. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II) : pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122 (4) :533-40.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  P2Y12 Receptor

• CAS Number:

  478005-11-7