(Rac) -BX 048

CAT: 0804-HY-W419570Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W419570Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Rac) -BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid (HY-109590) induced platelet aggregation (IC50 of 15 μM) [1].
CAS Number
[478005-11-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(O)CCC(NC(C1=NC2=CC(C)=CC=C2C(OC(C)(C)C(O)=O)=C1)=O)C(N3CCN(C(OCC)=O)CC3)=O
Molecular Formula
C27H34N4O9
Molecular Weight
558.58
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Post JM, et al. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II) : pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122 (4) :533-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y12 Receptor

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