Triisopropyl phosphate

• Description:

  Triisopropyl phosphate inhibits TFF1 and EGR3 gene expression, exhibits anti-estrogenic activity that inhibits Estradiol (HY-B0141) -induced MCF-7 cell proliferation with an EC50 of 341 μM. Triisopropyl phosphate inhibits the estrogen response element (ERE) -stimulated luciferase activity in MVLN cells with an EC50 of 900 μM[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H226, H315, H319, H335, H400

• Target:

  Estrogen Receptor/ERR

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Purity:

  98.0

• Smiles:

  O=P(OC(C)C)(OC(C)C)OC(C)C

• Molecular Formula:

  C9H21O4P

• Molecular Weight:

  224.23

• Precautions:

  H226, H315, H319, H335, H400

• References & Citations:

  [1]Li J, et al., Structure-Oriented Research on the Antiestrogenic Effect of Organophosphate Esters and the Potential Mechanism. Environ Sci Technol. 2020 Nov 17;54 (22) :14525-14534.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [513-02-0]