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4-MDM

CAT: 0804-HY-W097753-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W097753-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the Leukotriene A4 Hydrolase (LTA4H) aminopeptidase enzyme activity. 4-MDM reduces the neutrophil recruitment in the lung by enhancing the degradation of proline-glycine-proline by LTA4H, thereby reducing inflammation, and does not affect the epoxy-hydrolase activity of LTA4H. 4-MDM can be used for research on lung diseases[1].
CAS Number
834-14-0
Product Name Alternative
4-Methoxydiphenylmethane
UNSPSC
12352005
Hazard Statement
H315, H318, H400
Target
Aminopeptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.64
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C=C1)CC2=CC=CC=C2
Molecular Formula
C14H14O
Molecular Weight
198.26
Precautions
H315, H318, H400
References & Citations
[1]Farhan N, et al. Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation. J Pharm Biomed Anal. 2016 Sep 5;128:46-52.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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