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7,8-Dihydroxyflavone (Standard)

CAT: 0804-HY-W013372R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W013372R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF) . Displays therapeutic efficacy toward various neurological diseases[1].
CAS Number
38183-03-8
UNSPSC
12352005
Target
Apoptosis; Trk Receptor
Related Pathways
Apoptosis; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=C(O)C(O)=CC=C13
Molecular Formula
C15H10O4
Molecular Weight
254.24
References & Citations
[1]Zhang Z, et al. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology. 2014 Feb;39 (3) :638-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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