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3,6-Dihydroxyflavone

CAT: 0804-HY-N8481-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8481-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP) . 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].
CAS Number
108238-41-1
Product Name Alternative
3,6-DHF
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-6-dihydroxyflavone.html
Purity
99.45
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O=C1C(O)=C(C2=CC=CC=C2)OC3=CC=C(O)C=C13
Molecular Formula
C15H10O4
Molecular Weight
254.24
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648 (1-3) :31-38.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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