7,8-Dihydroxyflavone

• UNSPSC Description:

  7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1].

• Target Antigen:

  Apoptosis; Trk Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Neuronal Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/7,8-Dihydroxyflavone.html

• Purity:

  99.90

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C1C=C(C2=CC=CC=C2)OC3=C(O)C(O)=CC=C13

• Molecular Weight:

  254.24

• References & Citations:

  [1]Zhang Z, et al. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology. 2014 Feb;39(3):638-50.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  38183-03-8