Products for Research Use Only
RegisterLogin

Methyl succinate

CAT: 0804-HY-W010380-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W010380-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Methyl succinate is a mitochondrial complex II substrate. Methyl succinate can bypass the inhibition of complex I by Metformin , restore mitochondrial electron transfer, and reduce AMPK phosphorylation. Methyl succinate is capable of protecting MIN6 β-cells and primary rat β-cells from biguanide-induced toxicity and apoptosis in vitro. Methyl succinate can be used in the research of diseases such as diabetes mellitus[1].
CAS Number
3878-55-5
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Apoptosis
Related Pathways
Apoptosis; Epigenetics; PI3K/Akt/mTOR
Field of Research
Metabolic Disease
Concentration
10mM
Purity
99.78
Smiles
O=C(CCC(OC)=O)O
Molecular Formula
C5H8O4
Molecular Weight
132.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Hinke SA, et al. Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. Br J Pharmacol. 2007 Apr;150 (8) :1031-43
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150205-01Succinate/succinate receptor antagonist 1
HY-16170Desvenlafaxine (succinate)
HY-114458-01Monooctyl succinate
HY-A0069-01Doxylamine (succinate)
HY-Y0836-01Diethyl succinate
HY-135815A-01Mobocertinib (succinate)
HY-B1900-01Methylprednisolone succinate
HY-109091B-01Lanraplenib (succinate)
HY-115014Cibenzoline (succinate)
HY-B0121-01Sumatriptan succinate

Alternative Products

CatalogName
OR1058385-01Ethyl methyl succinate
M20060-01Methyl hydrogen succinate 97%
sc-236988Tert-Butyl methyl succinate
CS-T-94278O-Des Methyl Venlafaxine Succinate
OR1002547-011-Benzyl 4-methyl 2- (tert-butoxycarbonyl) succinate
AR-P02620-016-beta-Methyl Isomer of Methylhydrocortisone 21-Hydrogen Succinate
MBS6037166-01Sumatriptan Succinate (3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex,)
S8025-83Sumatriptan Succinate (3-[2- (Dimethylamino) ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex, )
CS-O-640462- (dimethylamino) ethyl (2- (methyl (nitroso) amino) ethyl) Succinate
MBS6031687-01Loxapine, Succinate (2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, Succinate)

Popular Products