NM-02

• Description:

  NM-02 is an antibody targeting HER2 with an EC50 value of 1.2 nM. NM-02 binds to domains I and II of HER2-ECD, blocking HER2-related signaling pathways. NM-02 is promising for research of HER2-positive breast cancer[1].

• UNSPSC:

  12352203

• Target:

  EGFR

• Related Pathways:

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  [N][M02]

• References & Citations:

  [1]Sawmynaden K, et al. Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool. PLoS One. 2023 Jul 17;18 (7) :e0288259.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Inhibitory Antibodies

• Clinical Information:

  No Development Reported

• Isoform:

  ErbB2/HER2