AMG-529

• Description :

  AMG-529 is a humanized anti-ASGR1 monoclonal antibody that binds to ASGR1 and blocks ligand binding, resulting in dose-induced increases in ALP, a biomarker of ASGR1 inhibition[1].

• UNSPSC :

  12352203

• Target :

  Phosphatase

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Purity :

  97.41

• Smiles :

  [AMG-529]

• References & Citations :

  [1]Janiszewski, M., et al. A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING SINGLE-DOSE, PHASE 1 STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF AMG 529, A NOVEL ANTI-ASGR1 MONOCLONAL ANTIBODY, IN HEALTHY SUBJECTS. Journal of the American College of Cardiology, 73 (9), 1755.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C

• Scientific Category :

  Inhibitory Antibodies

• Clinical Information :

  No Development Reported