AMG-529

CAT: 0804-HY-P991222-01Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-P991222-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-529 is a humanized anti-ASGR1 monoclonal antibody that binds to ASGR1 and blocks ligand binding, resulting in dose-induced increases in ALP, a biomarker of ASGR1 inhibition[1].
UNSPSC
12352203
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
97.41
Smiles
[AMG-529]
References & Citations
[1]Janiszewski, M., et al. A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING SINGLE-DOSE, PHASE 1 STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF AMG 529, A NOVEL ANTI-ASGR1 MONOCLONAL ANTIBODY, IN HEALTHY SUBJECTS. Journal of the American College of Cardiology, 73 (9), 1755.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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