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GRN-529

CAT: 0804-HY-124393Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124393Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats[1].
CAS Number
1253291-12-1
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/grn-529.html
Smiles
O=C(N1CC2=NC=CC=C2C1)C3=CC=C(C(C#CC4=NC=CC=C4)=C3)OC(F)F
Molecular Formula
C22H15F2N3O2
Molecular Weight
391.37
References & Citations
[1]Harvey BD, et al., Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors. Neuropharmacology. 2013 Dec;75:19-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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