Thromboxane B3

CAT: 0804-HY-113445-01Size: 25 μg (271.40 μM x 250 μL in Methyl Acetate)Dry Ice: NoHazardous: No
CAT#:0804-HY-113445-01Size:25 μg (271.40 μM x 250 μL in Methyl Acetate)
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Description
Thromboxane B3 is a prostaglandin analog derived from arachidonic acid (AA) in the cyclooxygenase (COX) metabolic pathway. Thromboxane B3 is generated from arachidonic acid (AA) in platelets and vascular endothelial cells through the catalysis of cyclooxygenase (COX) and thromboxane synthase (TXS) . Thromboxane B3 has been reported to be formed by human platelets upon ingestion of eicosapentaenoic acid (C20: 5ω3) [1][2].
CAS Number
[71953-80-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; Endogenous Metabolite
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/thromboxane-b3.html
Concentration
271.40 μM * 1 mL in Methyl acetate
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)C/C=C\CC)OC(O)C[C@@H]1O
Molecular Formula
C20H32O6
Molecular Weight
368.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Fischer S, et al. Thromboxane A3 (TXA3) is formed in human platelets after dietary eicosapentaenoic acid (C20: 5ω3) [J]. Biochemical and biophysical research communications, 1983, 116 (3) : 1091-1099.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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