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APL180 (TFA)

CAT: 0804-HY-P6365-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P6365-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APL180 TFA (L-4F) is an apolipoprotein AI mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL) . APL180 can be used in the study of cardiovascular diseases.
Product Name Alternative
L-4F (TFA)
UNSPSC
12352209
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
98.80
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC4=CC=CC=C4)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC(C)=O)CC(O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C114H156N24O28.xC2HF3O2
Molecular Weight
2310.60 (free base)
References & Citations
[1]Watson CE, et al. Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function. J Lipid Res. 2011 Feb;52 (2) :361-73.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2

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