Kiss2 peptide (acetate)

• UNSPSC Description:

  Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc)[1].

• Target Antigen:

  Kisspeptin Receptor; PKA; PKC

• Type:

  Peptides

• Related Pathways:

  Epigenetics;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/kiss2-peptide-acetate.html

• Purity:

  99.06

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](N)CC1=CC=CC=C1)N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC(N)=O.CC(O)=O.[x]

• Molecular Weight:

  1257.44 (free base)

• References & Citations:

  [1]Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported