NGX-267

• Description:

  NGX-267 is a selective agonist of the actin M1 receptor, which has high selectivity among the five actin receptor subtypes, especially for the M1 receptor rather than the M3 receptor. NGX-267 also has significant differences in affinity for dopamine D2 and 5-HT2B receptors[1].

• Product Name Alternative:

  AF-267B

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  MAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ngx-267.html

• Purity:

  99.17

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC[C@@H]1SC2 (CCN (CC2) C) NC1=O

• Molecular Formula:

  C10H18N2OS

• Molecular Weight:

  214.33

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  5-HT2 Receptor

• CAS Number:

  503431-81-0