NGX-267

• Description :

  NGX-267 is a selective agonist of the actin M1 receptor, which has high selectivity among the five actin receptor subtypes, especially for the M1 receptor rather than the M3 receptor. NGX-267 also has significant differences in affinity for dopamine D2 and 5-HT2B receptors[1].

• Product Name Alternative :

  AF-267B

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  MAChR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ngx-267.html

• Purity :

  99.17

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC[C@@H]1SC2(CCN(CC2)C)NC1=O

• Molecular Formula :

  C10H18N2OS

• Molecular Weight :

  214.33

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  5-HT2 Receptor

• CAS Number :

  [503431-81-0]