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DBCO-tag peptide P1

CAT: 0804-HY-P11316Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P11316Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBCO-tag peptide P1 is a cysteine-containing peptide tag. DBCO-tag peptide P1 selectively reacts with dibenzocyclooctyne (DBCO) to yield stable dibenzocyclooctenyl thioethers. DBCO-tag peptide P1 enables site-selective mEGFP labeling and antibody (such as Trastuzumab ) labelling without impairing the protein binding function. DBCO-tag peptide P1 can be used for ADC synthesis and mEGFP labeling research[1].
UNSPSC
12352209
Target
Biochemical Assay Reagents; Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Field of Research
Others
Smiles
O=C(N[C@@H](CS)C(N[C@@H](CC1=CC=C(C=C1)O)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](C(C)C)C(N[C@@H](CC5=CC=C(C=C5)O)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C48H62N8O10S
Molecular Weight
943.12
References & Citations
[1]Zhang C, et al. Site-Selective Cysteine-Cyclooctyne Conjugation. Angew Chem Int Ed Engl. 2018 May 28;57 (22) :6459-6463.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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