CP-EPS8-NLS

• Description :

  CP-EPS8-NLS is a peptide with anti-AML property. CP-EPS8-NLS interferes with EPS8-associated signaling and exerts anti-AML activity in various AML cell types. CP-EPS8-NLS has potent antitumor activity in xenograft tumor models. CP-EPS8-NLS downregulates EPS8 expression and its downstream pathway[1].

• UNSPSC :

  12352209

• Target :

  Complement System

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Cancer

• Smiles :

  O=C(C)NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N1[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](CO)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@H](CCCCN)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C130H249N61O29

• Molecular Weight :

  3130.76

• References & Citations :

  [1]Chen, Y., et al., (2018) . A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia. Journal of experimental & clinical cancer research : CR, 37 (1), 12.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported