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DV1 (TFA)

CAT: 0804-HY-P10427A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10427A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DV1 TFA is a selective antagonist for CXC chemokine receptor 4 (CXCR4) . DV1 TFA exhibits antiviral activity by blocking HIV-1 entry through the CXCR4 co-receptor[1].
UNSPSC
12352209
Target
CXCR; HIV
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
98.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H](N)CC(C)C)NCC(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N1[C@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(NCC(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N2[C@H](C(N[C@@H](C(N3[C@@H](C(N)=O)CCC3)=O)CC(C)C)=O)CCC2)=O)CCCNC(N)=N)=O)CCCCN)=O)CCC(N)=O)=O)CC4=CC=C(O)C=C4)=O)=O)CC(C)C)=O)CS)=O)CS)=O)CCCCN)=O)CC(O)=O)=O)CCC1)=O)CCCNC(N)=N)=O)CC5=CNC=N5)=O)CC6=CNC7=CC=CC=C67)=O)CO)=O)C)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C108H170N34O26S2.xC2HF3O2
Molecular Weight
2424.85 (free base)
References & Citations
[1]Zhu Y, et al., LC-MS/MS assay for the determination of a novel D-peptide antagonist of CXCR4 in rat plasma and its application to a preclinical pharmacokinetic study. J Pharm Biomed Anal. 2018 Nov 30;161:159-167.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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