Phleomycin G

• Description :

  Phleomycin G is a heteropeptide antibiotic. Phleomycin G has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin G extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin G inhibits airy entity carcinoma in mice[1].

• CAS Number :

  [11031-15-5]

• UNSPSC :

  12352211

• Target :

  Antibiotic; Bacterial

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Smiles :

  O=C(N)OC1C(C(OC2C(OC(C(C2O)O)CO)OC(C(C(NC(C(C(C)C(NC(C(C)O)C(NCCC3=NC(CS3)C4=NC(C(NCCCCNC(NCCCCNC(NCCCCNC(N)=N)=N)=N)=O)=CS4)=O)=O)O)C)=O)NC(C5=NC(C(CC(N)=O)NCC(C(N)=O)N)=NC(N)=C5C)=O)C6=CN=CN6)OC(C1O)CO)O

• Molecular Formula :

  C65H108N26O21S2

• Molecular Weight :

  1653.84

• References & Citations :

  [1]James B Wilson, et al. Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutat Res. 2010 Jul 7;689 (1-2) :12-20.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported