Phleomycin E

• Description :

  Phleomycin E is a heteropeptide antibiotic. Phleomycin E has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin E extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin E inhibits airy entity carcinoma in mice with an IC50 of 0.31 μg/mL[1].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Cancer; Infection

• Smiles :

  O=C(N)OC1C(C(OC2C(OC(C(C2O)O)CO)OC(C(C(NC(C(C(C)C(NC(C(C)O)C(NCCC3=NC(CS3)C4=NC(C(NCCCCNC(NCCCCNC(N)=N)=N)=O)=CS4)=O)=O)O)C)=O)NC(C5=NC(C(CC(N)=O)NCC(C(N)=O)N)=NC(N)=C5C)=O)C6=CN=CN6)OC(C1O)CO)O

• Molecular Formula :

  C60H97N23O21S2

• Molecular Weight :

  1540.68

• References & Citations :

  [1]R M Hall, et al. Identification and mapping of regions of the plasmid pKM101 which influence the growth rate and resistance to phleomycin E of Escherichia coli WP2. J Bacteriol. 1985 Sep;163 (3) :1142-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [11031-13-3]