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M-H2S

CAT: 0804-HY-D3003Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-D3003Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F₆₅₀/F₅₆₀) within the range of 0-40 μM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases[1].
CAS Number
2522921-17-9
UNSPSC
12352005
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
CC1(CC(/C=C/C2=CC=C(C=C2)OC(C3=CC=CC=C3C=O)=O)=C/C(C1)=C(C#N)\C#N)C
Molecular Formula
C27H22N2O3
Molecular Weight
422.48
References & Citations
[1]Shu W, et al. An Endoplasmic Reticulum-Targeted Ratiometric Fluorescent Probe for the Sensing of Hydrogen Sulfide in Living Cells and Zebrafish. Anal Chem. 2020 Jul 21;92 (14) :9982-9988.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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