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Sgc8c-M

CAT: 0804-HY-177571Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177571Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sgc8c-M is a PTK7-targeted aptamer-drug conjugate (ApDC). Sgc8c-M is composed of the classic PTK7-specific aptamer Sgc8c, a cathepsin B (CTSB) -cleavable valine-citrulline (VC) -based linker, and the potent antimitotic agent Monomethyl auristatin E (MMAE) as the payload. Sgc8c-M inhibits the growth of PTK7-overexpressing cancer cells. Sgc8c-M can be used for the study of PTK7-expressing advanced solid tumors[1].
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
[Sgc8c-M]
References & Citations
[1]Su M, et al. An aptamer-drug conjugate for promising cancer therapy with comprehensive evaluation from rodents to non-human primates. Signal Transduct Target Ther. 2025 Sep 24;10 (1) :316.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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