Debrisoquin (hydrobromide)

• Description:

  Debrisoquine (Ro 5-3307/1) hydrobromide is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquine hydrobromide can be used for antiviral research[1].

• Product Name Alternative:

  Debrisoquine (hydrobromide) ; Isocaramidine (hydrobromide) ; Ro 5-3307/1 (hydrobromide)

• UNSPSC:

  12352005

• Target:

  SARS-CoV; Ser/Thr Protease

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Smiles:

  N=C(N1CC2=C(CC1)C=CC=C2)N.Br

• Molecular Formula:

  C10H14BrN3

• Molecular Weight:

  256.14

• References & Citations:

  [1]Amanda L. Peiffer, et.al.TMPRSS2 Inhibitor Discovery Facilitated through an In Silico and Biochemical Screening Platform.ACS Medicinal Chemistry Letters 2023 14 (6), 860-866.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1131-65-3]