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Debrisoquin

CAT: 0804-HY-B1624-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1624-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin can be used for antiviral research[1].
CAS Number
1131-64-2
Product Name Alternative
Debrisoquine; Isocaramidine; Ro 5-3307/1
UNSPSC
12352005
Target
SARS-CoV; Ser/Thr Protease
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Debrisoquin.html
Solubility
10 mM in DMSO
Smiles
NC(N1CCC2=C(C1)C=CC=C2)=N
Molecular Formula
C10H13N3
Molecular Weight
175.23
References & Citations
[1]Amanda L. Peiffer, et.al.TMPRSS2 Inhibitor Discovery Facilitated through an In Silico and Biochemical Screening Platform.ACS Medicinal Chemistry Letters 2023 14 (6), 860-866.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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