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Mephenytoin-d3

CAT: 0804-HY-B1184S-01Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1184S-01Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Rac) -Mephenytoin-d3 is a labelled racemic Mephenytoin. Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate[1].
CAS Number
1185101-86-3
UNSPSC
12352005
Target
Cytochrome P450; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(C)C1(C(=O)N(C([2H])([2H])[2H])C(=O)N1)C2=CC=CC=C2
Molecular Formula
C12H11D3N2O2
Molecular Weight
221.27
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Klaassen T, et al. Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. Eur J Clin Pharmacol. 2008;64 (4) :387-398.|[3]Relling MV, et al. Mephenytoin phenotyping: lack of haematologic effect and timing of urine collections. Pharmacogenetics. 1991;1 (1) :42-49.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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