Mephenytoin

• UNSPSC Description:

  Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mephenytoin.html

• Purity:

  99.96

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;warming)

• Smiles:

  O=C1N(C)C(C(C2=CC=CC=C2)(CC)N1)=O

• Molecular Weight:

  218.256

• References & Citations:

  [1]Klaassen T, et al. Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. Eur J Clin Pharmacol. 2008;64(4):387-398.|[2]D R Minck, et al. Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology. 1991 Apr;43(4):279-93. |[3]J H Maguire, et al. Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice. Eur J Pharmacol. 1985 Oct 29;117(1):135-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  50-12-4