Products for Research Use Only
RegisterLogin

Domperidone-13C6

CAT: 0804-HY-B0411S2Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0411S2Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Domperidone-13C6 (R33812-13C6) is 13C labeled Domperidone. Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1].
Product Name Alternative
R33812-13C6
UNSPSC
12352005
Target
Dopamine Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1NC2=CC(Cl)=CC=C2N1C3CCN(CCCN(C(NC)=O)C)CC3.[13CH]4=[13CH][13CH]=[13CH][13CH]=[13CH]4
Molecular Formula
C18 13C6H32ClN5O2
Molecular Weight
463.95
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Reddymasu SC, et al. Domperidone: review of pharmacology and clinical applications in gastroenterology. Am J Gastroenterol. 2007;102 (9) :2036-2045.|[3]Champion MC, et al. Domperidone, a new dopamine antagonist. CMAJ. 1986;135 (5) :457-461.|[4]Stoetzer C, et al. Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels. Anesth Analg. 2017 Jan. 124 (1) :52-60.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0411-01Domperidone
HY-B0411A-01Domperidone (monomaleate)
HY-B0411R-01Domperidone (Standard)
HY-B0411S-01Domperidone-d6
HY-B0411ARDomperidone (monomaleate) (Standard)
HY-W778408-01Tamoxifen-13C6
HY-W777496-01Saccharin-13C6
HY-W756637Ibufenac-13C6
HY-W777457Anthracene-13C6
HY-W777526Nitisinone-13C6

Alternative Products

CatalogName
CS-EK-00576Domperidone 13C6
CS-EK-00631Domperidone-N-oxyde 13C6
B1481-5.1Domperidone

Popular Products