AMCA

• Description:

  AMCA (4- (Aminomethyl) -1-cyclohexanecarboxylic acid) is a PROTAC linker. AMCA can be used to synthesize the PROTAC molecule YB-3–17 (HY-170405) [1].

• Product Name Alternative:

  4- (Aminomethyl) -1-cyclohexanecarboxylic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H319

• Target:

  PROTAC Linkers

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Purity:

  98.0

• Solubility:

  H2O : 87.5 mg/mL (ultrasonic)

• Smiles:

  O=C(C1CCC(CN)CC1)O

• Molecular Formula:

  C8H15NO2

• Molecular Weight:

  157.21

• Precautions:

  H319

• References & Citations:

  [1]Liu Y, et al., A Dual-Target and Dual-Mechanism Design Strategy by Combining Inhibition and Degradation Together. J Am Chem Soc. 2024 Dec 2.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [701-54-2]