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Asenapine impurity 1

CAT: 0804-HY-75405Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-75405Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Asenapine impurity 1 is an impurity of Asenapine. Asenapine, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder[1][2].
CAS Number
165890-26-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Neurological Disease
Purity
95.0
Smiles
O=C1[C@](C(C=C(Cl)C=C2)=C2OC3=C4C=CC=C3)([H])[C@]4([H])CN1C
Molecular Formula
C17H14ClNO2
Molecular Weight
299.76
Precautions
H302, H315, H319, H335
References & Citations
[1]M Shahid, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23 (1) :65-73. |[2]Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl) . 2008 Feb;196 (3) :417-29.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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