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PDGFR-IN-2

CAT: 0804-HY-42933-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-42933-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDGFR-IN-2 (Compound 16C) is a 4-phenoxyquinoline derivative. PDGFR-IN-2 is a platelet-derived growth factor receptor (PDGFr) inhibitor (IC50: 0.20 μM) . PDGFR-IN-2 inhibits the activity of PDGFr tyrosine kinase[1].
CAS Number
190728-25-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PDGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.97
Solubility
DMSO : 9.09 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCL; heat to 60°C)
Smiles
NC1=CC=C(OC2=CC=NC3=CC(OC)=C(OC)C=C23)C=C1
Molecular Formula
C17H16N2O3
Molecular Weight
296.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Kubo K, et al. Synthesis and structure-activity relationship for new series of 4-phenoxyquinoline derivatives as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase. Bioorg Med Chem. 2003 Nov 17;11 (23) :5117-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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