Dasatinib intermediate-1

• Description:

  Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181) . Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bcr-Abl

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Purity:

  98.0

• Smiles:

  O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl

• Molecular Formula:

  C16H13Cl2N5OS

• Molecular Weight:

  394.28

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Distler JH, et al. Intracellular tyrosine kinases as novel targets for anti-fibrotic therapy in systemic sclerosis. Rheumatology (Oxford) . 2008 Oct;47 Suppl 5:v10-1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [302964-08-5]