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Dasatinib intermediate-1

CAT: 0804-HY-41940-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-41940-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib. Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity[1].
CAS Number
302964-08-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Purity
98.0
Smiles
O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl
Molecular Formula
C16H13Cl2N5OS
Molecular Weight
394.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Distler JH, et al. Intracellular tyrosine kinases as novel targets for anti-fibrotic therapy in systemic sclerosis. Rheumatology (Oxford) . 2008 Oct;47 Suppl 5:v10-1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported