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(3S,4R) -Tofacitinib

CAT: 0804-HY-40354B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-40354B-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(3S,4R) -Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
CAS Number
1092578-48-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/_3S,4R_-Tofacitinib.html
Solubility
10 mM in DMSO
Smiles
CN(C1=NC=NC2=C1C=CN2)[C@H]3[C@H](C)CCN(C(CC#N)=O)C3
Molecular Formula
C16H20N6O
Molecular Weight
312.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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