KRP-105

CAT: 0804-HY-19852Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19852Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRP-105 is a potent, highly selective, and orally effective PPAR alpha (EC50 = 8 nM) agonist. KRP-105 can significantly reduce serum triglyceride, total cholesterol, and non high density lipoprotein cholesterol levels. KRP-105 can be used for research on metabolic diseases such as dyslipidemia[1].
CAS Number
[876145-69-6]
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
OC(C1=CC=CC(N(CCC2)C[C@H]2NC(C3=C(C)N=C(C4=CC=C(C=C4)Cl)S3)=O)=C1)=O
Molecular Formula
C23H22ClN3O3S
Molecular Weight
455.96
References & Citations
[1]Nomura M, et al. Discovery of cyclic amine-substituted benzoic acids as PPARα agonists. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :334-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα

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