IDX-320

• Description:

  IDX-320 is a Pipecolic acid (HY-Y0669) derivative. IDX-320 inhibits NS3/4a proteases across genotypes 1a, 1b, 2a, and 4a with an IC50 0.8-1.9 nM. IDX-320 can be used in the research of HCV infection[1].

• UNSPSC:

  12352005

• Target:

  Drug Derivative; HCV Protease

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease; Others

• Field of Research:

  Infection

• Smiles:

  O=C(NS(=O)(C1(CC1)C)=O)[C@]23NC([C@@](C[C@@H](OC4=CC(C5=NC(C(F)(F)F)=CS5)=NC6=C(C)C(OC)=CC=C46)CC7)([H])N7C(N(C)CCCC/C=C\[C@]2([H])C3)=O)=O

• Molecular Formula:

  C37H43F3N6O7S2

• Molecular Weight:

  804.90

• References & Citations:

  [1]Liverton N J. Evolution of HCV NS3/4a Protease Inhibitors[M]//HCV: The Journey from Discovery to a Cure: Volume I. Cham: Springer International Publishing, 2019: 231-259.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [1251165-81-7]