Ro-09-4889

• Description:

  Ro-09-4889 is a prodrug. Ro-09-4889 can inhibit DPD activity and its effect is dose-dependent. Ro-09-4889 can be used for cancer research[1].

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  C[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](N2C(N=C(C(C=C)=C2)N)=O)O1

• Molecular Formula:

  C15H19N3O6

• Molecular Weight:

  337.33

• References & Citations:

  [1]Bellibas SE, et al. Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clin Cancer Res. 2004 Apr 1;10 (7) :2327-35.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [216449-60-4]