KW-4490

• Description:

  KW-4490 is a selective phosphodiesterase 4 (PDE4) inhibitor. KW-4490 can be used for the researches of inflammation and immunology, such as asthma[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Smiles:

  COC(C1=C2OCCO1)=CC=C2[C@]3(C#N)CC[C@@H](C(O)=O)CC3

• Molecular Formula:

  C17H19NO5

• Molecular Weight:

  317.34

• References & Citations:

  [1]Fujita K, et al. Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys. Xenobiotica. 2008 May;38 (5) :511-26.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  PDE4

• CAS Number:

  [260561-48-6]