KW-8232

• Description :

  KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2[1].

• UNSPSC :

  12352005

• Target :

  Prostaglandin Receptor; SARS-CoV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/kw-8232.html

• Purity :

  98.10

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(N1CCN(CC1)C2=C(Cl)C=CC=C2)C3=C(C(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)C6=C(N3CCN(C)C)C=CC=C6.O=S(O)(C)=O

• Molecular Formula :

  C37H41ClN4O6S

• Molecular Weight :

  705.26

• References & Citations :

  [1]Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78 (2) :241-3.|[2]Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EP

• CAS Number :

  [217813-15-5]