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KW-2449

CAT: 0931-T2341-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2341-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1000669-72-6
Target
C-Kit, Aurora Kinase, JAK, Apoptosis, FLT, FGFR, Src, Bcr-Abl
Related Pathways
Cell Cycle/Checkpoint, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, JAK/STAT signaling, Apoptosis
Purity
0.9989
Bioactivity
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.
Smiles
O=C(N1CCNCC1)c1ccc(C=Cc2n[nH]c3ccccc23)cc1
Molecular Formula
C20H20N4O
Molecular Weight
332.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

1000669-72-6

PubChem
cas1000669-72-6
modify2026-05-17
description[4-[2-(1H-indazol-3-yl)ethenyl]phenyl]-(1-piperazinyl)methanone is a member of indazoles.
synonyms
KW-24491000669-72-6KW 2449KW2449UNII-2D9N67F58GKW 2449 [WHO-DD]
(4-((1E)-2-(1H-Indazol-3-yl)ethenyl)phenyl)-1-piperazinylmethanone
Methanone, [4-[2-(1H-indazol-3-yl)ethenyl]phenyl]-1-piperazinyl-
Piperazine, 1-(4-((1E)-2-(1H-indazol-3-yl)ethenyl)benzoyl)-
3-[(E)-2-{4-[(piperazin-1-yl)carbonyl]phenyl}ethenyl]-2H-indazole
+ 15 more
PubChem LinkClick here

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CatalogName
A4123-10KW 2449
HY-10339-01KW-2449

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