KW-2449

• Target:

  C-Kit|||Aurora Kinase|||JAK|||Apoptosis|||FLT|||FGFR|||Src|||Bcr-Abl

• Related Pathways:

  Cell Cycle/Checkpoint|||Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Stem Cells|||JAK/STAT signaling|||Apoptosis

• Purity:

  0.9989

• Bioactivity:

  KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFR?, IGF-1R, EGFR.

• Smiles:

  O=C(N1CCNCC1)c1ccc(C=Cc2n[nH]c3ccccc23)cc1

• Molecular Formula:

  C20H20N4O

• Molecular Weight:

  332.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1000669-72-6