KW-2449

• Target :

  C-Kit|||Aurora Kinase|||JAK|||Apoptosis|||FLT|||FGFR|||Src|||Bcr-Abl

• Related Pathways :

  Cell Cycle/Checkpoint|||Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Stem Cells|||JAK/STAT signaling|||Apoptosis

• Purity :

  0.9989

• Bioactivity :

  KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFR?, IGF-1R, EGFR.

• Smiles :

  O=C(N1CCNCC1)c1ccc(C=Cc2n[nH]c3ccccc23)cc1

• Molecular Formula :

  C20H20N4O

• Molecular Weight :

  332.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1000669-72-6