OGT-719

CAT: 0804-HY-19272Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19272Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OGT-719 is a potent, orally active nucleoside analogue that targets the asialoglycoprotein receptor (ASGP-R) . OGT-719 inhibits growth of metastatic colorectal tumors in the liver of nude mice. OGT-719 can be used for primary hepatocellular carcinoma and colorectal liver metastases research[1].
CAS Number
[185843-61-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Asialoglycoprotein Receptor (ASGPR) ; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(C(F)=CN1[C@H]2[C@@H]([C@H]([C@H]([C@@H](CO)O2)O)O)O)=O
Molecular Formula
C10H13FN2O7
Molecular Weight
292.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Rohlff C, et al. A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C170HM2. Cancer Res. 1999 Mar 15;59 (6) :1268-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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