BM 170249

CAT: 0804-HY-19227Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19227Size:1 Each
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Description
BM 170249 is a peroxisome proliferator, particularly in the perivenous region of the central acini in the liver. BM 170249 significantly reduces serum triglyceride and cholesterol levels in rats. BM 170249 strongly induces the activity of key enzymes in the peroxisome fatty acid β-oxidation system (such as acyl-CoA oxidase AOX, multifunctional enzyme PH, and thiolase PT), but leads to decreased activity of catalase and uricase in peroxisome components. BM 170249 could be used in lipid-lowering studies[1].
CAS Number
[153655-35-7]
UNSPSC
12352211
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cardiovascular Disease
Smiles
O=C(O)C(Cl)(Cl)CCCCCCCCCCC(Cl)(Cl)C(O)=O
Molecular Formula
C14H22Cl4O4
Molecular Weight
396.13
References & Citations
[1]Lindauer M, et al. Zonal heterogeneity of peroxisomal enzymes in rat liver: differential induction by three divergent hypolipidemic drugs. Hepatology. 1994 Aug;20 (2) :475-86.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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