NAT6-297775

• Description :

  NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia[1].

• UNSPSC :

  12352005

• Target :

  Phosphatase; SHP2

• Related Pathways :

  Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

• Field of Research :

  Cancer

• Smiles :

  N(CC1CCCCC1)[C@H]2O[C@@]3([C@H](CO[C@@]3(C2)[H])N4C(=NN=N4)C5=CC(CN6CCCC6)=CC=C5)[H]

• Molecular Formula :

  C25H36N6O2

• Molecular Weight :

  452.60

• References & Citations :

  [1]Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19 (7) :2145-55.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1348433-02-2]