NAT2-IN-1

• Description:

  NAT2-IN-1 (APA) is an inhibitor of agent metabolic enzyme N-acetyltransferase 2 (NAT2) . NAT2-IN-1 can selectively kill slow NAT2 cells[1].

• Product Name Alternative:

  APA

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Histone Acetyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nat2-in-1.html

• Purity:

  99.0

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C(OC)C(OC)=CC(NC2=NC(C3=CC=C(N)C=C3)=CN=C2)=C1

• Molecular Formula:

  C19H20N4O3

• Molecular Weight:

  352.39

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Rendo V, et, al. Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy. Nat Commun. 2020 Mar 11;11 (1) :1308.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [856005-97-5]