TT-012-Br

• Description:

  TT-012-Br (Compound 4) is a ligand for MITF and can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for Target Protein for PROTAC; Microphthalmia Associated Transcription Factor (MITF)

• Related Pathways:

  Cell Cycle/DNA Damage; PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C(NC1=NC(NC(/C=C/C2=CC=CO2)=O)=CC(Br)=C1)/C=C/C3=CC=CO3

• Molecular Formula:

  C19H14BrN3O4

• Molecular Weight:

  428.24

• References & Citations:

  [1]Shen W, et al. Discovery of a first-in-class degrader for microphthalmia-associated transcription factor (MITF) . Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118367.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported