L-012

• Description:

  L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox) -derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS) ) [1][2].

• UNSPSC:

  12352005

• Target:

  Fluorescent Dye

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/l-012.html

• Purity:

  99.63

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(C1=C2C(Cl)=NC(C3=CC=CC=C3)=C1N)NNC2=O

• Molecular Formula:

  C13H9ClN4O2

• Molecular Weight:

  288.69

• References & Citations:

  [1]Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47 (6) :760-766.|[2]Imada I, et al. Analysis of reactive oxygen species generated by neutrophils using a chemiluminescence probe L-012[J]. Analytical biochemistry, 1999, 271 (1) : 53-58.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  143323-55-1