L-012

• Description :

  L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox) -derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS) ) [1][2].

• UNSPSC :

  12352005

• Target :

  Fluorescent Dye

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/l-012.html

• Purity :

  99.63

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=C2C(Cl)=NC(C3=CC=CC=C3)=C1N)NNC2=O

• Molecular Formula :

  C13H9ClN4O2

• Molecular Weight :

  288.69

• References & Citations :

  [1]Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47 (6) :760-766.|[2]Imada I, et al. Analysis of reactive oxygen species generated by neutrophils using a chemiluminescence probe L-012[J]. Analytical biochemistry, 1999, 271 (1) : 53-58.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [143323-55-1]