CDK2-IN-43

• Description :

  CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. CDK2-IN-43 can be used in the research of the anti-cancer field[1].

• UNSPSC :

  12352005

• Target :

  CDK

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Smiles :

  CC1=CC(C)=C(CNC2=C3C(N(C)C=N3)=NC(N[C@@H](CO)C(C)C)=N2)C=N1

• Molecular Formula :

  C19H27N7O

• Molecular Weight :

  369.46

• References & Citations :

  [1]Zhang Y, et al. Development of 9H-purine scaffold as novel CDK2 inhibitors: Design, synthesis, and biological evaluation. Bioorg Med Chem Lett. 2025 Mar 7;122:130166.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK2