HCA I-IN-2

CAT: 0804-HY-147986Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147986Size:1 Each
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Description
HCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with Ki values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively[1].
CAS Number
[2417232-12-1]
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hca-i-in-2.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)N2C=C(N=N2)CN3C=C(C4=CC=CC=C43)/C=C/C(C5=CC=C(C=C5)Br)=O)=O
Molecular Formula
C26H20BrN5O3S
Molecular Weight
562.44
References & Citations
[1]Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA I

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