Products for Research Use Only
RegisterLogin

FLT3-IN-35

CAT: 0804-HY-178908Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-178908Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FLT3-IN-35 (Compound 4K) is an orally active, covalent, irreversible FLT3 inhibitor. FLT3-IN-35 inhibits the phosphorylation of FLT3 and its downstream signaling factors, as well as induces cell cycle arrest and apoptosis. FLT3-IN-35 inhibits the phosphorylation of FLT3 and its downstream signaling factors, as well as induced cell cycle arrest and apoptosis. FLT3-IN-35 can be used for the study of acute myeloid leukemia (AML) [1].
UNSPSC
12352005
Target
Apoptosis; FLT3
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CN(CC1)CCN1C(C(C)=C2)=CC=C2NC3=NC=C4C(C(C5=CC=CC=C5NC(C=C)=O)=CC=C4)=N3
Molecular Formula
C29H30N6O
Molecular Weight
478.59
References & Citations
[1]Wei W, et al. Design, synthesis and biological evaluation of 8-phenylquinazolin-2-amine derivatives as FLT3 covalent inhibitors targeting cysteine 828 in the ATP pocket. Eur J Med Chem. 2026 Jan 5;301:118212.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-178996FLT3-IN-36
HY-178020FLT3-IN-34
HY-174911FLT3-IN-33
HY-174437FLT3-IN-32
HY-170640FLT3-IN-29
HY-112387FLT3-IN-26
HY-112366FLT3-IN-38
HY-162032FLT3-IN-25
HY-156410FLT3-IN-23
HY-18744-01FLT3-IN-2

Alternative Products

CatalogName
GTR19273661-01FLT3-IN-35
316201FLT3
BNUM2458-50Flt3 / CD135 (FLT3/2458), 1mg/mL
E2252308Flt3-L/Flt3 Ligand Rabbit pAb
BA8968-5FLT3-IN-6
BA8964-1FLT3-IN-3
BA8971-10FLT3-IN-19
BA8963-100FLT3-IN-2
BA8972-5FLT3-IN-10
BA8969-5.1FLT3-IN-4

Popular Products