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EGFR ligand-18

CAT: 0804-HY-178313Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178313Size:1 Each
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Description
EGFR ligand-18 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC EGFR degrader 16. PROTAC EGFR degrader 16 is a potent EGFR PROTAC degrader with anti-tumor activity[1].
UNSPSC
12352005
Target
EGFR; Ligands for Target Protein for PROTAC
Related Pathways
JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=NC=CS1)C(C2=C(CCC3)N3C=N2)N(CC4=C5C=C(C6=CC=CC=C6)C=C4F)C5=O
Molecular Formula
C25H20FN5O2S
Molecular Weight
473.52
References & Citations
[1]Christopher G, et al. EGFR DEGRADERS TO TREAT CANCER METASTASIS TO THE BRAIN OR CNS CROSS-REFERENCE TO RELATED APPLICATIONS. WO2022251539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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